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Collaborative Studies

COSMIC: Cohort Studies of Memory in an International Consortium; UNSW Sydney

  • COSMIC website
  • 2017 - present
  • Principal Investigator: Perminder Sachdev AM, MBBS, MD, PhD, FRANZCP, FAAHMS
    Scientia Professor of Neuropsychiatry
    Centre for Healthy Brain Ageing (CHeBA)
    University of New South Wales
    Sydney, Australia
  • An international consortium to combine data from population-based longitudinal cohort studies including MYHAT to identify common risk factors for dementia and cognitive decline.

Click here for a list of collaborative publications using MYHAT and MoVIES data.

MYHAT-Neuroimaging; University of Pittsburgh, PA

  • 2017 - 2022
  • Principal Investigator: Beth E. Snitz, PhD
    Associate Professor of Neurology
    University of Pittsburgh School of Medicine
    Pittsburgh, PA, USA
  • A neuroimaging study which enrolled a subgroup of MYHAT participants for baseline and 2.5-year follow-up MRI, amyloid-PET and tau-PET scans.

Click here for a list of collaborative publications using MYHAT and MoVIES data.

MOVE-MYHAT; University of Pittsburgh, PA

  • Neurobiological Drivers of Mobility Resilience: The Dopaminergic System
  • 2018 - 2023
  • NIA grant #U01AG061393
  • Multiple Principal Investigators:
    • Caterina Rosano, MD, MPH
      Professor of Epidemiology
      University of Pittsburgh School of Public Health
      Pittsburgh, PA, USA
    • Andrea L Rosso, PhD, MPH
      Associate Professor of Epidemiology
      University of Pittsburgh School of Public Health
      Pittsburgh, PA, USA
  • This is a longitudinal study, including a subcohort of MYHAT participants, to test the hypothesis that the striatal dopaminergic (DA) system provides resilience against the detrimental effects of common locomotor risk factors, via its connections with sensorimotor networks, thus favoring automated motor control and less engagement of attentional and prefrontal resources; we also propose a small translational study to collect pilot data on L-DOPA related changes in sensorimotor DA networks and gait. 

Click here for a list of collaborative publications using MYHAT data.