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MYHAT: Scientific Reports Published

2025
Abstract  | Full Article  | Thirumala PD, Snitz BE, Jacobsen E, Chang C-C H, Chang YF, Ganguli M.  Long-term cognitive trajectories in older adults after surgery: a population-based study. Alzheimer’s Disease and Associated Disorders 2025, ePub: DOI: 10.1097/WAD.0000000000000655. PMID 39781640, NIHMS2092531, PMC in process. [online ahead of print]
Abstract  | Full Article  | Acharya, V., Fan, K. H., Snitz, B. E., Ganguli, M., DeKosky, S. T., Lopez, O. L., Feingold, E., & Kamboh, M. I. (2025). Sex-stratified genome-wide meta-analysis identifies novel loci for cognitive decline in older adults. Alzheimer's & dementia : the journal of the Alzheimer's Association, 21(3), e14461. https://doi.org/10.1002/alz.14461.  PMID: 40042063;  PMCID: 11880917
Abstract  | Full Article  | Editorial  |  Ganguli, M., Jacobsen, E., Song, R., Wood, I., Kinnee, E. J., Hughes, T. F., Snitz, B. E., & Chang, C. H. (2024). Social determinants of health and mild cognitive impairment in a diverse community sample. Journal of the American Geriatrics Society, 10.1111/jgs.19251. Advance online publication. https://doi.org/10.1111/jgs.19251; PMID: 39563463; PMCID 11826000
Abstract  | Full Article  | Hughes TF, Song R, Wang Y, Jacobsen E, Chang C-C H, Ganguli M.  The Impact of the COVID-19 Pandemic on Symptoms of Depression and Anxiety among Older Adults: The MYHAT Study. Aging and Mental Health, 2025 in press.   PMC in process.
2024
Abstract  | Full Article  | Weinstein, A.M., Fang, F. Chang, C., Cohen, A., Lopresti, B.J., Laymon, C.M., Nadkarni, N.K.,  Aizenstein, H.J., Villemagne, V.L, Kamboh, M.I., Shaaban, C.E., Gogniat, M.A., Wu, M., Karikari, T.K., Ganguli, M., Snitz, B.E. (accepted). Multimodal neuroimaging biomarkers and subtle cognitive decline in a population-based cohort without dementia. Journal of Alzheimer’s Disease, doi: 10.1177/13872877241303926. NIHMS 2030086, PMID: 39702989, PMCID: PMC11798718
Abstract  | Full Article  | Zeng X; Lafferty TK;  Sehrawat A;  Chen Y;  Ferreira PCL Bellaver B; Povala G, Kamboh MI; Klunk WE; Cohen AD;  Lopez OL, Ikonomovic M; Pascoal T, Ganguli M, Villemagne VD; Snitz BE, Karikari, TK.  Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer’s disease. Molecular Neurodegeneration 2024,  DOI: 10.1186/s13024-024-00753-5, PMID: 39385222, PMCID: PMC11465638   
Abstract  | Full Article  | De Genna NM, Jacobsen E, Ganguli M. Marijuana use among community-dwelling older adults: A population-based study. Int J Geriatr Psychiatry. 2024 Apr;39(4):e6086. doi: 10.1002/gps.6086. PMID: 38613138. PMC in process.
Abstract  | Full Article  |  Zhang Y, Ferreira PCL, Jacobsen E,  Bellaver B, Pascoal TA, Snitz BE, Chang C-C H, Villemagne VL, Ganguli M, Karikari T.  Association of plasma biomarkers of Alzheimer’s disease and related disorders with cognition and cognitive decline: a population-based study. Alzheimer’s & Dementia, 2024, ePub doi: 10.1002/alz.13829. PMID 38753951, PMC in process. 
Abstract  | Full Article  |  Research Poster  |  Wood IK, Song R, Zhang Y, Jacobsen E, Hughes T, Chang C-C H, Ganguli M. Ethno-racial identity and cognitive impairment: A community study. Alzheimer’s Disease and Associated Disorders, 2024, DOI 10.1097/WAD.0000000000000617, PMID 38748688,  PMC: 11536525
2023
Abstract  | Full Article  |  Gonzalez-Ortiz, F., Ferreira, P. C. L., González-Escalante, A., Montoliu-Gaya, L., Ortiz-Romero, P., Kac, P. R., Turton, M., Kvartsberg, H., Ashton, N. J., Zetterberg, H., Harrison, P., Bellaver, B., Povala, G., Villemagne, V. L., Pascoal, T. A., Ganguli, M., Cohen, A. D., Minguillon, C., Contador, J., Suárez-Calvet, M., … Blennow, K. (2024). A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association, 20(2), 1239–1249. https://doi.org/10.1002/alz.13525; PMID 37975513; PMCID 10916963
Abstract  | Full Article  |  Fang, F., Hughes, T. F., Weinstein, A., Dodge, H. H., Jacobsen, E. P., Chang, C. H., Snitz, B. E., & Ganguli, M. (2023). Social Isolation and Loneliness in a Population Study of Cognitive Impairment: The MYHAT Study. Journal of applied gerontology : the official journal of the Southern Gerontological Society, 42(12), 2313–2324. https://doi.org/10.1177/07334648231192053; PMID:37518906, PMCID 10825064
Abstract  | Full Article  |  Teverovsky EG, Gildengers A, Ran X, Jacobsen E, Chang C-C H, Ganguli M. Benzodiazepine use and risk of incident MCI and dementia in a community sample.  International Psychogeriatrics, 2023,  ePub DOI: https://doi.org/10.1017/S1041610223000455   PMID 37231775, NIHMSID 1904514, PMCID: PMC10676448 
Abstract  | Full Article  |  Bellaver, B., Povala, G., Ferreira, P. C. L., Ferrari-Souza, J. P., Leffa, D. T., Lussier, F. Z., Benedet, A. L., Ashton, N. J., Triana-Baltzer, G., Kolb, H. C., Tissot, C., Therriault, J., Servaes, S., Stevenson, J., Rahmouni, N., Lopez, O. L., Tudorascu, D. L., Villemagne, V. L., Ikonomovic, M. D., Gauthier, S., … Pascoal, T. A. (2023). Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease. Nature medicine, 29(7), 1775–1781. https://doi.org/10.1038/s41591-023-02380-x; PMID:37248300, PMCID 10353939
Abstract  | Full Article  |  Jain N, Wang Y, Zhang Y, Jacobsen E, Andreescu C, Snitz BE, Chang C-C H, Ganguli M. It goes both ways: The relationship between anxiety and mild cognitive impairment.  International Journal of Geriatric Psychiatry, 2023, e5899, ePub  http://doi.org/10.1002/gps.5899   PMID:36855309 PMCID: 11531759
Abstract  | Full Article  |  Ferreira PCL, Zhang Y, Snitz B, Chang C-C H, Bellaver B, Jacobsen EP, Kamboh MI, Zetterberg H, Blennow K, Pascoal T, Villemagne V, Ganguli M, Karikari T.  Plasma biomarkers identify older adults at risk of Alzheimer’s disease and related dementias in a real-world population cohort.  Alzheimer’s & Dementia, 2023;19(10):4507-4519. doi:10.1002/alz.12986; PMID: 36876954; PMCID 10480336
Abstract  |  Full Article  |  Gildengers AG, Stoehr GP, Ran X, Jacobsen EP, Teverovsky EG, Chang C-C H, Ganguli M. Anticholinergic drug burden and risk of incident MCI and dementia –A Population-Based Study. Alzheimer’s Disease and Associated Disorders, 2022, DOI: 10.1097/WAD.0000000000000538, PMID: 36706325; PMCID 9974875
Abstract  |  Full Article  |  Wood I, Bhojak T, Jia Y, Jacobsen EP, Snitz BE, Chang C-C H, Ganguli M.  Predictors of driving cessation in older adults: A 12-year population-based study.  Alzheimer’s Disease and Associated Disorders, 2022, DOI: 10.1097/WAD.0000000000000541, PMID: 36706321; PMCID 9974810
Abstract  |  Full Article  | Acharya V, Fan KH, Snitz BE, et al. Meta-analysis of age-related cognitive decline reveals a novel locus for the attention domain and implicates a COVID-19-related gene for global cognitive function [published online ahead of print, 2023 Apr 23]. Alzheimer's & Dementia: the journal of the Alzheimer's Association. 2023;10.1002/alz.13064. PMID: 37089073; PMCID 10590825; doi:10.1002/alz.13064
2022
Abstract  | Full Article  |  Fan, K., Francis, L., Aslam, M. M., Bedison, M. A., Lawrence, E., Acharya, V., Snitz, B. E., Ganguli, M., DeKosky, S. T., Lopez, O. L., Feingold, E., & Kamboh, M. I. (2023). Investigation of the independent role of a rare APOE variant (L28P; APOE*4Pittsburgh) in late-onset Alzheimer disease. Neurobiology of aging, 122, 107–111. PMID: 36528961; PMCID: 9839598 ; https://doi.org/10.1016/j.neurobiolaging.2022.11.007
Abstract  | Full Article  |  Hughes TF, Ran X, Fang F, et al. Psychosocial implications of early COVID-19 restrictions on older adults in a small-town region in Southwestern, Pennsylvania (USA) [published online ahead of print, 2022 Nov 10]. Int Psychogeriatr. 2022;1-10. PMID: 36352761; doi:10.1017/S1041610222000977
Abstract  | Full Article  |  Lee S, Jia Y, Snitz B, Chang C-C H, Ganguli M.  Assessing social cognition in older adults: A population-based study.  Alzheimer’s Disease and Associated Disorders, 2022.  EPub doi: 10.1097/WAD.0000000000000497.  PMID 35288520.  PMC 9149050.
2021
Abstract  |  Full Article  |  Runk A, Jia Y, Liu A, Chang CH, Ganguli M, Snitz BE. Associations between Visual Acuity and Cognitive Decline in Older Adulthood: A 9-Year Longitudinal Study. J Int Neuropsychol Soc. 2023;29(1):1-11. PMID: 36630994; PMCID: 9834646; doi:10.1017/S1355617721001363
Abstract  |  Full Article  | Sullivan K, Ran X, Wu F, Chang C-C H, Sharma R, Jacobsen E, Berman S. Ambient fine particulate matter exposure and incident mild cognitive impairment and dementia. Journal of the American Geriatrics Society. PMID: 33904156; PMCID: 8373708; doi: https://doi.org/10.1111/jgs.17188
Abstract  |  Full Article  | Bhojak T, Jia Y, Jacobsen E, Snitz BE, Chang C-C H, Ganguli M. Driving Habits of older adults: A Population-Based Study. Alzheimer Disease and Associated Disorders. PMID: 33769988; PMCID: 8387314; DOI: 10.1097/WAD.0000000000000443
Abstract  |  Full Article  | Jacobsen, E., Ran, X., Liu, A., Chang, C. H., & Ganguli, M. (2021). Predictors of attrition in a longitudinal population-based study of aging. International psychogeriatrics, 33(8), 767–778. PMID: 32301414; PMCID: 7572515; doi: 10.1017/S1041610220000447
Abstract  |  Full Article  | Hughes TF, Liu A, Jacobsen E, et al. Exercise and the Risk of Mild Cognitive Impairment: Does the Effect Depend on Vascular Factors? Alzheimer Dis Assoc Disord. 2021;35(1):30-35; PMID: 32960854; PMCID9350907; doi:10.1097/WAD.0000000000000410
2020
Abstract  |  Full Article  |  Ganguli M, Hughes TF, Jia Y, Lingler J, Jacobsen E, Chang CH. Aging and Functional Health Literacy: A Population-based Study [ePub ahead of print], 2020. Am J Geriatr Psychiatry. 2020;S1064-7481(20)30575-3. PMID: 33349506; doi:10.1016/j.jagp.2020.12.007
Abstract  |  Full Article  | Lee S, Jacobsen EP, Jia Y, Snitz BE, Chang CH, Ganguli M. Reading the Mind in the Eyes: A Population-Based Study of Social Cognition in Older Adults . Am J Geriatr Psychiatry. 2020;S1064-7481(20)30562-5. PMID: 33293250; PMCID: 8166961; doi:10.1016/j.jagp.2020.11.009
Abstract  |  Full Article  | Sullivan KJ, Liu A, Chang CH, et al. Alzheimer's disease pathology in a community-based sample of older adults without dementia: The MYHAT neuroimaging study [ePub ahead of print]. Brain Imaging Behav. 2020;10.1007/s11682-020-00334-2. PMID: 32748322; PMCID: 7855234; doi:10.1007/s11682-020-00334-2
Abstract  |  Full Article  | Fan KH, Feingold E, Rosenthal SL, Demirci Y, Ganguli M, Lopez OL, Kamboh MI. Whole-Exome Sequencing (WES) Analysis of Alzheimer's Disease in Non-APOE*4 Carriers. Journal of Alzheimers Disease. 2020;76(4):1553-1565. PMID: 32651314; PMCID: 7484092; doi: 10.3233/JAD-200037
Abstract  |  Full Article  | Jia Y., Chang, C. C. H., Hughes, T. F., Jacobsen, E., Wang, S., Berman, S. B., Kamboh, M. I., & Ganguli, M. Predictors of Dementia in the Oldest Old: a Novel Machine Learning Approach. [ePub ahead of print]. Alzheimer Dis Assoc Discord. 2020;10.1097; PMID: 32701513; PMCID: 7677183; doi: doi:10.1097/WAD.0000000000000400
Abstract  |  Full Article  | Cohen AD, Jia Y, Smagula S, Chang C-C H, Snitz B, Berman SB, Jacobsen EP, Ganguli M. Cognitive functions predict trajectories of sleepiness over ten years: A population-based study. [ePub ahead of print]. 2020; J Gerontol A Biol Sci Med Sci. PMID: 32405646; PMCID: 7907493; doi: 10.1093/gerona/glaa120;
Abstract  |  Full Article  | Ganguli M, Beer JC, Zmuda JM, Ryan CM, Sullivan KJ, Chang, CC, Rao RH. Aging, diabetes, obesity, and cognitive decline: A Population-Based Study. [ePub ahead of print] Journal of the American Geriatrics Society. 2020;68(5):991-998. PMID: 32020605; PMCID: 8597580; doi: 10.1111/jgs.16321
Abstract  |  Full Article  | Peters R, Beers JC, Ganguli M, Anstey KJ.  Investigation of antihypertensive class, dementia and cognitive decline.  A meta-analysis. Neurology. 2020;94(3):e267-281. PMCID: 7108807; PMID: 31827004; doi: 0.1212/WNL.0000000000008732
Abstract  |  Full Article  | Sullivan KJ, Liu A, Dodge HH, Andreescu C, Chang CCH, Ganguli M. Depression Symptoms Declining Among Older Adults: Birth Cohort Analyses from the Rust Belt. American Journal of Geriatric Psychiatry. 2020; 28(1):99-107. PMID: 31300193 PMCID: 6898763; doi: 10.1016/j.jagp.2019.06.002
Abstract  |  Full Article  | Smagula SF, Jia Y, Chang CH, Cohen A, Ganguli M. Trajectories of daytime sleepiness and their associations with dementia incidence. Journal of Sleep Research. 2020; 29(6):e12952. PMID: 31782578; PMCID: 7253318; doi:10.1111/jsr.12952
Abstract  |  Full Article  | Stoehr GP, Jacobsen EP, Jia Y, Snitz BE, Ganguli M. Trends in the use of medications and supplements to treat or prevent dementia: A population-based study. Alzheimer Disease and Associated Disorders 2020, 34(2):148-155; ePub 2019 doi: 10.1097/WAD.0000000000000357, PMID 31633558, PMC7156330.
Abstract  |  Full Article  | Hughes TF, Beer JC, Jacobsen EP, Ganguli M, Chang, Chung-Chou, Rosano C. Executive function predicts decline in mobility after a fall: The MYHAT Study. Experimental Gerontology 2020, 14;137:110948. doi: 10.1016/j.exger.2020.110948. PMID: 32302664, PMC 7299804
2019
Abstract  |  Full Article  | Liu A, Sun Z, McDade E, Hughes TF, Ganguli M, Chang CH. Blood Pressure and Memory. Novel Approaches to Modeling Nonlinear Effects in Longitudinal Studies.  Alzheimer Disease and Associated Disorders. 2019;33(4):291-298. PMID: 31567145; PMCID: 6878165. doi: 10.1097/WAD.0000000000000346
Abstract  |  Full Article  | Kamboh MI, Fan KH, Yan Q, Beer J, Snitz BE, Wang X, Chang CH, Demirci FY, Feingold E, Ganguli M.  Population-based genome-wide association study of cognitive decline in older adults free of dementia: Identification of a novel locus for the attention domain.  Neurobiology of Aging. 2019;84:239. PMID: 30954325; PMCID: 6739197; doi: 10.1016/j.neurobiolaging.2019.02.024
Abstract  |  Full Article  | Ganguli M, Jia Y, Hughes TF, Snitz BE, Chang CH, Berman SB, Sullivan KJ, Kamboh MI.  Mild cognitive impairment that does not progress to dementia: A population-based study.  Journal of the American Geriatrics Society. 2019;67(2):232-238. PMCID: 6367026; PMID: 30444944; doi: 10.1111/jgs.15642
Abstract  |  Full Article  | Sullivan KJ, Dodge HH, Hughes TF, Chang CH, Zhu X, Liu A, Ganguli M. Declining Incident Dementia Rates Across Four Population-Based Birth Cohorts. Journal of Gerontology Series A: Biological and Medical Sciences. 2019;74(9):1439-1445. PMID: 30312371; PMCID: 6696712; doi: 10.1093/gerona/gly236
Abstract  |  Full Article  | Shaaban CE, Jia Y, Chang C-C H, Ganguli M. Independent and joint effects of vascular and cardiometabolic risk factor pairs for risk of all-cause dementia: a prospective population-based study. International Psychogeriatrics, 2019; ePub doi: 10.1017/S1041610219001066 . PMID 31455442. PMC 6948010
2018
Abstract  |  Full Article  | Snitz BE, Wang T, Cloonan YK, Jacobsen E, Chang CH, Hughes TF, Kamboh MI, Ganguli M.  Risk of progression from subjective cognitive decline to mild cognitive impairment: The role of study setting.  Alzheimers & Dementia. 2018;14(6);734-742. PMID: 29352855; PMCID: 5994356; doi:  10.1016/j.jalz.2017.12.003
Abstract  |  Full Article  | Beer J, Snitz BE, Chang C-C H., Loewenstein D, Ganguli M.  Does a cognitive stress test predict progression from mild cognitive impairment to dementia equally well in clinical versus population-based settings?  International Psychogeriatrics. 2018;30(10):1435-1445. PMCID: 6047940; PMID: 29335040; doi: 10.1017/S1041610217002666
Abstract  |  Full Article  | Ganguli M, Sun Z, McDade E, Snitz BE, Hughes TF, Jacobsen E, Chang CC.  That's Inappropriate!  Social Norms in an Older Population-Based Cohort.  Alzheimer Disease and Associated Disorders. 2018;32(2):150-155. PMCID: 5951726; PMID: 29140857; doi: 10.1097/WAD.0000000000000224
Abstract  |  Full Article  | Hughes TF, Sun Z, Chang CH, Ganguli M.  Change in engagement in cognitive activity and risk for mild cognitive impairment in a cohort of older adults: The Monongahela-Youghiogheny Healthy Aging Team (MYHAT) study. Alzheimer Disease and Associated Disorders. 2018;32(2):137-144; PMID: 29028647; PMCID: 10317197; doi: 10.1097/WAD.0000000000000224
2017
Abstract  |  Full Article  | Dodge HH, Zhu J, Hughes TF, Snitz BE, Chang CH, Jacobsen EP, Ganguli M. Cohort effects in verbal memory function and practice effects: A population-based study. International Psychogeriatrics. 2017;29(1):137-148. PMCID: 5177461; PMID: 27725002; doi: 10.1017/S1041610216001551
2016
Abstract  |  Full Article  | McDade E, Sun Z, Lee CW, Snitz BE, Hughes T, Change CC, Ganguli M. The association between pulse pressure change and cognition in late life: Age and where you start matters. Alzheimer's & Dementia: Diagnosis, Assessment, and Disease Monitoring. 2016;4:55-66. PMCID: 4961825; PMID: 27489881; doi: 10.1016/j.dadm.2016.03.008
Abstract  |  Full Article  | Nimgaonkar VL, Yolken RH, Wang T, Chang CC, McClain L, McDade E, Snitz BE, Ganguli M. Temporal cognitive decline associated with exposure to infectious agents in a population-based, aging cohort. Alzheimer Disease and Associated Disorders. 2016;30(3):216-222. PMCID: 4919236; PMID: 26710257; doi: 10.1097/WAD.0000000000000133
Abstract  |  Full Article  | Graziane JA, Beer JC, Snitz BE, Chang CC, Ganguli M. Dual trajectories of cognition and depression: A longitudinal population study. American Journal of Geriatric Psychiatry. 2016;24(5):364-373. PMCID: 4841743; PMID: 26560510; doi: 10.1016/j.jagp.2015.08.001
2015
Abstract  |  Full Article  | Snitz BE,  Small BJ, Wang T, Chang CC, Hughes TF, Ganguli M. Do subjective memory complains lead or follow objective cognitive change? A Five-Year Population Study of Temporal Influence.  Journal of the International Neuropsychological Society. 2015;21(9):732-42. PMCID: 4615611; PMID: 264776801; doi: 10.1017/S1355617715000922
Abstract  |  Full Article  | Hughes TF, Becker JT, Lee CW, Chang CC, Ganguli M. Independent and combined effects of cognitive and physical activity on incident MCI. Alzheimers and Dementia. 2015;11(11):1377-1384. PMCID: 4536189; PMID: 25684687; doi: 10.1016/j.jalz.2014.11.007
Abstract  |  Full Article  | Ganguli M, Lee C-W, Snitz BE, Hughes TF, McDade E, Chang C-CH. Rates and risk factors for progression to incident dementia vary by age in population cohort. Neurology. 2015;84(1):72-80. PMCID: 4336092; PMID: 25471390; doi: 10.1212/WNL.0000000000001113
Abstract  |  Full Article  | Ganguli M, Lee C-W, Hughes TF, Snitz BE, Jakubcak J, Duara R, Chang C-CH. Who wants a free brain scan? Assessing and correcting for recruitment biases in a population-based sMRI pilot study. Brain Imaging and Behavior. 2015;9(2):204-212. PMCID: 4147027; PMID: 24573773; doi: 10.1007/s11682-014-9297-9
2014
Abstract  |  Full Article  | Ganguli M, Lee C-W, Snitz BE, Hughes TF, McDade E, Chang CC. How well do MCI Criteria predict progression to severe cognitive impairment and dementia? Alzheimer Disease Associated Disorders. 2014;28(2):113-121. PMCID: 4040213; PMID: 24521821; doi: 10.1097/WAD.0000000000000018
Abstract  |  Full Article  | Hughes TF, Flatt JD, Fu B, Butters MA, Chang CC, Ganguli M. Interactive video gaming compared with health education in older adults with mild cognitive impairment: a feasibility study. International Journal of Geriatric Psychiatry. 2014;29(9):890-898. PMCID: 4326259; PMID: 24452845; doi: 10.1002/gps.4075
Abstract  |  Full Article  | Ganguli M, Fu B, Snitz BE, Unverzagt FW, Loewenstein DA, Hughes TF, Chang CC. Vascular risk factors and cognitive decline in a population sample. Alzheimer Disease and Associated Disorders. 2014;28(1):9-15. PMCID: 3945071; PMID: 24126216; doi: 10.1097/WAD.0000000000000004
Abstract  |  Full Article  | Andreescu C, Teverovsky E, Fu B, Hughes TF, Chang CC, Ganguli M. Old worries and new anxieties - behavioral symptoms and mild cognitive impairment in a population study. American Journal of Geriatric Psychiatry. 2014;22(3):274-284. PMCID: 3783616; PMID: 23759435; doi: 10.1016/j.jagp.2012.09.010
Abstract  |  Full Article  | Dodge HH, Zhu J, Lee CW, Chang CC, Ganguli M. Cohort effects in age-associated cognitive trajectories. J Gerontol A Biol Sci Med Sci. 2014;69(6):687-694. PMID: 24270062; PMCID: 4022091; doi:10.1093/gerona/glt181
2013
Abstract  |  Full Article  | Ganguli M, Fu B, Snitz BE, Hughes TF, Chang CC. Mild cognitive impairment: incidence and vascular risk factors in a population-based cohort. Neurology. 2013;80(23):2221-2120. PMCID: 3716350; PMID: 23658380; doi: 10.1212/WNL.0b013e318295d776
Abstract  |  Full Article  | Hughes TF, Flatt JD, Fu B, Chang CC, Ganguli M. Engagement in social activities and progression from mild to severe cognitive impairment: The MYHAT study. International Psychogeriatrics. 2013;25(4):587-595. PMCID: 3578022; PMID: 23257280; doi: 10.1017/S1041610212002086
2012
Abstract  |  Full Article  | Becker JT, Duara R, Lee C-W, Teverovsky L, Snitz BE, Chang C-CH, Ganguli M. Cross-validation of brain structural biomarkers and cognitive aging in a community-based study. International Psychogeriatrics. 2012;24(7):1065-1075. PMCID: 3391579; PMID: 22420888; doi: 10.1017/S1041610212000191
Abstract  |  Full Article  | Snitz BE, Yu L, Crane PK, Chang CC, Hughes TF, Ganguli M.  Subjective cognitive complaints of older adults at the population level: an Item Response Theory analysis. Alzheimer Disease and Associated Disorders. 2012;36(4):344-351. PMCID: 3337955; PMID: 22193355; doi: 10.1097/WAD.0b013e3182420bdf
Abstract  |  Full Article  | Hughes TF, Chang C-CH, Vander Bilt J, Snitz BE, Ganguli M. Mild cognitive deficits and everyday functioning among older adults in the community: The Monongahela-Youghiogheny Healthy Aging Team (MYHAT) Study. American Journal of Geriatric Psychiatry. 2012;20(10):836-844. PMCID: 3445790; PMID: 22337146; doi: 10.1097/JGP.0b013e3182423961
2011
Abstract  |  Full Article  | Ganguli M, Snitz BE, Saxton JA, et al. Outcomes of mild cognitive impairment by definition: a population study.  Archives of Neurology. 2011;68(6):761-767. PMCID: 3135309; PMID: 21670400; doi: 10.1001/archneurol.2011.101
Abstract  |  Full Article  | Weir, D. R., Wallace, R. B., Langa, K. M., Plassman, B. L., Wilson, R. S., Bennett, D. A., Duara, R., Loewenstein, D., Ganguli, M., & Sano, M. (2011). Reducing case ascertainment costs in U.S. population studies of Alzheimer's disease, dementia, and cognitive impairment-Part 1. Alzheimer's & dementia : the journal of the Alzheimer's Association, 7(1), 94–109. PMCID: 3044596; PMID: 21255747; doi: 10.1016/j.jalz.2010.11.004
Abstract  |  Full Article  | Knopman, D. S., Petersen, R. C., Rocca, W. A., Larson, E. B., & Ganguli, M. (2011). Passive case-finding for Alzheimer's disease and dementia in two U.S. communities. Alzheimer's & dementia : the journal of the Alzheimer's Association, 7(1), 53–60. PMCID: PMC3137259; PMID: 21255743; doi: https://doi.org/10.1016/j.jalz.2010.11.001
2010
Abstract  |  Full Article  | Ganguli M, Vander Bilt J, Lee C-W, Snitz BE, Chang CC, Loewenstein DA, Saxton JA. Cognitive test performance predicts change in functional status at the population level: The MYHAT project. Journal of the International Neuropsychological Society. 2010;16(5):761-770. PMCID: 3232179; PMID: 20609270; doi: 10.1017/S1355617710000561
Abstract  |  Full Article  | Ganguli M, Chang C-CH, Snitz BE, Saxton JA, Vander Bilt J, Lee C-W. (2010). Prevalence of Mild Cognitive Impairment by multiple classifications. The Monongahela-Youghiogheny Healthy Aging Team (MYHAT) Project. American Journal of Geriatric Psychiatry. 2010;18(8):674-683. PMCID: 2906673; PMID: 20220597; doi: 10.1097/JGP.0b013e3181cdee4f
Abstract  |  Full Article  | Snitz BE, Loewenstein DA, Chang CC, Lee C-W, Vander Bilt J, Saxton J, Ganguli M. A novel approach to assessing memory at the population level: Vulnerability to semantic interference. International Psychogeriatrics. 2010;22(5):785-794. PMCID: 2891858; PMID: 20105350; doi: 10.1080/13607860903071014
Abstract  |  Full Article  | Ganguli M, Snitz BE, Lee C-W, Vanderbilt J, Saxton JA, Chang CC. Age and education effects and norms on a cognitive test battery from a population-based cohort:  The Monongahela-Youghiogheny Healthy Aging Team (MYHAT).  Aging and Mental Health. 2010;14(1):100-107. PMCID: 2828360; PMID: 20155526; doi: 10.1080/13607860903071014
Abstract  |  Full Article  | Kamboh, M. I., Minster, R. L., Demirci, F. Y., Ganguli, M., Dekosky, S. T., Lopez, O. L., & Barmada, M. M. (2012). Association of CLU and PICALM variants with Alzheimer's disease. Neurobiology of aging, 33(3), 518–521. PMCID: PMC3010357; PMID: 20570404; doi: https://doi.org/10.1016/j.neurobiolaging.2010.04.015
2009
Abstract  |  Full Article  | Snitz BE, Unverzagt FW, Chang CC, Vander Bilt J, Gao S, Saxton J, Hall KS, Ganguli M. Effects of age, gender, education, and race on two tests of language ability in community-based older adults. International Psychogeriatrics. 2009;21(6):1051-1062. PMCID: 2783556; PMID: 19586563; doi: 10.1017/S1041610209990214
Abstract  |  Full Article  | Ganguli M, Snitz B, Vander Bilt J, Chang CC. How much do depressive symptoms affect cognition at the population level? The Monongahela-Youghiogheny Healthy Aging Team (MYHAT) study. International Journal of Geriatric Psychiatry. 2009;24(11):1277-1284. PMCID: 2784260; PMID: 19340894; doi: 10.1002/gps.2257