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MYHAT: Collaborative Projects

Please visit our Collaborative Studies page for more information about each project.

MYHAT-Neuroimaging; University of Pittsburgh, PA

2024
Abstract  |  Full Article  |  Weinstein AM, Fang F, Chang C-C H, Cohen A, Lopresti BJ, Laymon CM, Nadkarni NK, Aizenstein HJ, Villemagne VL, Kamboh MI, Shaaban CE, Gogniat M, Wu M, Karikari TK, Ganguli M, Snitz BE.   Multimodal neuroimaging biomarkers and subtle cognitive decline in a population-based cohort without dementia, Journal of Alzheimer’s Disease 2024, ePub  doi: 10.1177/13872877241303926,  PMID: 39702989,  PMC11798718.
2023
Abstract  |  Full Article  |   Bellaver B, Povala G, Ferreira PCL,…. Ganguli M, Karikari TK, Rosa-Neto P, Pascoal TA.  Astrocyte reactivity influences the association of amyloid-β and tau biomarkers in preclinical Alzheimer’s disease.  Nature Medicine, 2023 doi: 10.1038/s41591-023-02380-x.  PMID 37248300,  PMC10353939
2021
Abstract  |  Full Article  |   Sullivan KJ, Liu A, Chang C-CH, Cohen AD, Lopresti BJ, Minhas DS, Laymon CM, Klunk WE, Aizenstein HJ, Nadkarni NK, Loewenstein DA, Kamboh MI, Ganguli M, Snitz BE.  Alzheimer’s Disease Pathology in a Community-Based Sample of Older Adults Without Dementia: The MYHAT Neuroimaging Study. Brain Imaging and Behavior, 2021,15(3):1355-1363. ePub 2020, doi:10.1007/s11682-020-00334-2, PMID: 32748322,PMC7855234.

MOVE-MYHAT; University of Pittsburgh, PA

2025
Abstract  | Full Article  |  Chahine LM, Rosse A, Troidl I, Ganguli M, Newman A, Cummings S, Studentski S, Lopresti B, Royse S, Huppert T, Refern M, Sparto PJ, Bohnen N, Rosano C.  Nigrostriatal Dopaminergic Neurotransmission and Resilience to Peripheral Systemic Risk Factors for Gait Slowing upon Transition to Uneven Surfaces in Older Adult. Aging Brain, 2025, in press.  PMC in process. 
Abstract  | Full Article  |  Chahine LM, Rosso AL, Troidl I, Ganguli M, Newman A, Lopresti B, Royse S, Mosovsky S, Ratner E, Dholakia G, Bohnen N, Rosano C. Features of Prodromal Parkinson's Disease and Dopaminergic Neurotransmission in Community Dwelling Older Adults. Neurology 2025, in press. PMC in process
Abstract  | Full Article  | Rosso AL, Baillargeon EM, Bohnen NI, Lopresti BJ, Huppert TJ, Chahine LM, Jacobsen E, Rosano C. Nigrostriatal dopaminergic integrity in relation to prefrontal cortex activity and gait performance during dual-task walking in older adults. Journal of Gerontology: Medical Sciences, 2025 Jun 23, in press.

COSMIC: Cohort Studies of Memory in an International Consortium; UNSW Sydney

2025
Abstract  | Full Article  | Van Asbroeck S, Kohler S, van Boxtel MPJ,… Ganguli M, Hughes T, Jacobsen E,… Sachdev P, Deckers K, for Cohort Studies of Memory in an International Consortium (COSMIC) (2024). Lifestyle and incident dementia: a COSMIC individual participant data meta-analysis. Alzheimer's & dementia : the journal of the Alzheimer's Association. 10.1002/alz.13846. Advance online publication. https://doi.org/10.1002/alz.13846. PMID 38676366.
2024
Abstract  | Full Article  | Lo JW, Crawford JD, Lipnicki DM,….Ganguli M, Jacobsen E, Snitz BE… Sachdev, PS. Trajectory of cognitive decline before and after stroke in 14 population cohorts: a COSMIC study. JAMA Network Open, 2024, 7(10):e2437133, doi: 10.1001/jamanetworkopen.2024.37133, PMID 39356504, PMC11447567
Abstract  | Full Article  | Zhao X, Xu X, Yan Y….Ganguli M, Jacobsen EP, Chang C-C H …for Cohort Studies of Memory in an International Consortium (COSMIC). Independent and Joint Associations of Cardiometabolic Multimorbidity and Depression on Cognitive Function: Findings from Multi-regional Cohorts and Generalization from Community to Clinic. Lancet Regional Western Pacific, 2024, ePub DOI: https://doi.org/10.1016/j.lanwpc.2024.101198, PMID 39308753; PMCID 11416683
2023
Abstract  | Full Article  | Gong, J., Harris, K., Lipnicki, D. M., Castro-Costa, E., Lima-Costa, M. F., Diniz, B. S., Xiao, S., Lipton, R. B., Katz, M. J., Wang, C., Preux, P. M., Guerchet, M., Gbessemehlan, A., Ritchie, K., Ancelin, M. L., Skoog, I., Najar, J., Sterner, T. R., Scarmeas, N., Yannakoulia, M., … Cohort Studies of Memory in an International Consortium (COSMIC) (2023). Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium. Alzheimer's & dementia : the Journal of the Alzheimer's Association, 19(8), 3365–3378. https://doi.org/10.1002/alz.12962; PMID 36790027
2022
Abstract  |  Full Article  |  Wu, W., Ding, D., Zhao, Q., Xiao, Z., Luo, J., Ganguli, M., Hughes, T. F., Jacobsen, E., Haan, M. N., van Dang, K., Lima-Costa, M. F., Blay, S. L., de Castro-Costa, E., Ng, T. P., Gwee, X., Gao, Q., Gureje, O., Ojagbemi, A., Bello, T., Shahar, S., … for Cohort Studies of Memory in an International Consortium (COSMIC) (2022). Dose-response relationship between late-life physical activity and incident dementia: A pooled analysis of 10 cohort studies of memory in an international consortium. Alzheimer's & dementia : the journal of the Alzheimer's Association, 10.1002/alz.12628. Advance online publication. https://doi.org/10.1002/alz.12628
Abstract  |  Full Article  |  Mewton, L., Visontay, R., Hoy, N., Lipnicki, D. M., Sunderland, M., Lipton, R. B., Guerchet, M., Ritchie, K., Najar, J., Scarmeas, N., Kim, K. W., Riedel Heller, S., van Boxtel, M., Jacobsen, E., Brodaty, H., Anstey, K. J., Haan, M., Scazufca, M., Lobo, E., Sachdev, P. S., and Collaborators from the Cohort Studies of Memory in an International Consortium (COSMIC) (2022). The relationship between alcohol use and dementia in adults aged more than 60 years: a combined analysis of prospective, individual-participant data from 15 international studies. Addiction (Abingdon, England), 10.1111/add.16035. Advance online publication. https://doi.org/10.1111/add.16035; PMID35993434
2020
Abstract  |  Full Article  |  Carles S, Carrière I, Reppermund S, et al. A cross-national study of depression in preclinical dementia: A COSMIC collaboration study. Alzheimers Dement. 2020;16(11):1544-1552. PMID: 32881298; doi:10.1002/alz.12149. PMC7666102
Abstract  |  Full Article  |  Samtani S, Mahalingam G, Lam BCP, Lipnicki DM, Lima-Costa MF, Blay SL, Castro-Costa E, Shifu X, Guerchet M, Preux PM, Gbessemehlan A, Skoog I, Najar J, Rydberg Sterner T, Scarmeas N, Kim KW, Riedel-Heller S, Röhr S, Pabst A, Shahar S, Numbers K, Ganguli M, Jacobsen E, Hughes TF, Crowe M, Ng TP, Maddock J, Marseglia A, Mélis R, Szcześniak D, Wiegelmann H, Vernooij-Dassen M, Jeon YH, Sachdev PS, Brodaty H; SHARED consortium for the Cohort Studies of Memory in an International Consortium (COSMIC). Associations between social connections and cognition: a global collaborative individual participant data meta-analysis. Lancet Healthy Longev. 2022 Nov;3(11):e740-e753. doi: 10.1016/S2666-7568(22)00199-4. Epub 2022 Oct 20. PMID: 36273484; PMCID: PMC9750173.
Abstract  |  Full Article  |  Mahalingam G, Samtani S… Ganguli M, Hughes TF, Chang C-C H… Perminder S Sachdev, Henry Brodaty on behalf of the SHARED consortium for the Cohort Studies of Memory in an International Consortium (COSMIC). Social connections and risk of incident mild cognitive impairment, dementia and mortality in 13 longitudinal cohort studies of ageing. Alzheimer's & Dementia, 2023, ePub https://doi.org/10.1002/alz.13072. PMID 37102417
2019
Abstract  |  Full Article  |  Hyun J, Hall CB, Katz MJ, Derby CA, Lipnicki DM, Crawford JD, Guaita A, Vaccaro R, Davin A, Kim KW, Han JW, Bae JB, Rohr S, Riedl-Heller S, Ganguli M, Jacobsen E, Hughes TF, Brodaty H, Kochan NA, Trollor J, Lobo A, Santabarbara J, Lopez-Anton R, Sachdev PS, Lipton RB. Education, Occupational Complexity, and Incident Dementia: A COSMIC Collaborative Cohort Study. Journal of Alzheimer's disease 2021, ePub DOI: 10.3233/JJournal of Alzheimer's Disease. PMID: 34776437; PMC 8748312.

Other Collaborations

2020
Abstract  |  Full Article  |  Imperial College, London  |  Peters R, Beers JC, Ganguli M, Anstey KJ. Investigation of antihypertensive class, dementia and cognitive decline. A meta-analysis. Neurology. 2020;94(3):e267-281. PMCID: 7108807; PMID: 31827004; doi: 0.1212/WNL.0000000000008732
2019
Abstract  |  Full Article  |  City University of New York, Brooklyn College  |  Asperholm M, Högman N, Rafi J, Herlitz A. What did you do yesterday? A meta-analysis of sex differences in episodic memory. Psychol Bull. 2019;145(8):785-821. PMID: 31180695; doi:10.1037/bul0000197
2018
Abstract  |  Full Article  |  Harvard University  |  Darweesh SKL, Wolters FJ, Ikram MA, de Wolf F, Bos D, Hofman A. Inflammatory markers and the risk of dementia and Alzheimer's disease: A meta-analysis. Alzheimers Dement. 2018;14(11):1450-1459. PMID: 29605221; doi:10.1016/j.jalz.2018.02.014
2017
Abstract  |  Full Article  |  Sunnybrook Health Science Centre  |  Au B, Dale-McGrath S, Tierney MC. Sex differences in the prevalence and incidence of mild cognitive impairment: A meta-analysis. Ageing Res Rev. 2017;35:176-199. PMID: 27771474; doi:10.1016/j.arr.2016.09.005
Abstract  |  Full Article  |  City University of New York, Brooklyn College  |  Molinuevo JL, Rabin LA, Amariglio R, et al. Implementation of subjective cognitive decline criteria in research studies. Alzheimers Dement. 2017;13(3):296-311. PMID: 27825022; PMCID: 5344703; doi:10.1016/j.jalz.2016.09.012
2015
Abstract  |  Full Article  |  City University of New York, Brooklyn College  |  Rabin LA, Smart CM, Crane PK, et al. Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies. J Alzheimers Dis. 2015;48 Suppl 1(0 1):S63-S86. PMID: 26402085; PMCID: 4617342; doi:10.3233/JAD-150154
2013
INNDI Link  |  Johns Hopkins Medicine  |  Project Name: International Neuropsychological Normative Database Initiative (INNDI)